Did you know that Windows NT, XP, 2K3, etc.. do not automatically defragment the hard drive? Excessive file fragmentation can seriously impact performance.
NT didn't even include a defragment utility, but XP and 2k3 have both a GUI and a command line version. The GUI is very nice, if you remember to run it, but I always forget. It's best to have it set to do an automatic defragment every night. The GUI version can't do that, but the command line version can, if you know the trick.
Just setup a scheduled task to Run: %SystemRoot%\system32\cmd.exe /C defrag C: in the middle of the night.
You can schedule a task under Start / Control Panel / Performance and Maintenance / Scheduled Tasks.
You can test it by right clicking on the new scheduled task and selecting Run.