With sealing under pressure, I'd be looking for ways to drop the internal p= ressure, thermally or by pump or ??. You probably could do a seal under light positive internal pressure, but I = think it wouldn't be pretty. -----Original Message----- From: piclist-bounces@mit.edu [mailto:piclist-bounces@mit.edu] On Behalf Of= William Westfield Sent: Wednesday, November 1, 2017 7:35 PM To: Microcontroller discussion list - Public. Subject: Re: [EE] Vacuum plumbing > I've done some sealing of volatile liquids (elemental Bromine) in pyrex a= mpoules and I found it very challenging to get a technique down. I would imagine that the issues with sealing evacuated glassware are somewh= at different than sealing an ampoule with contents at or above 1Atm. In th= e vacuum case, you have atmospheric pressure on your side... BillW -- http://www.piclist.com/techref/piclist PIC/SX FAQ & list archive View/chang= e your membership options at http://mailman.mit.edu/mailman/listinfo/piclis= t --=20 http://www.piclist.com/techref/piclist PIC/SX FAQ & list archive View/change your membership options at http://mailman.mit.edu/mailman/listinfo/piclist .