> We stand on the bridge at Khazad-d=FBm. The not distant = > enough drums sound > their doom-doom call ... I was impressed and pleased at the range of responses to = that post. Many of the implications have been nicely = unearthed. > = > http://www.wired.com/science/discoveries/news/2008/01/synthetic_genome?cu= rrentPage=3Dall Nobody gave the Balrog or the bridge a second mention though = :-). FWIW it needs to be realised that Craig Venter is arguably = the most capable person on earth to produce results in this = field, bust because of his person knowledge and experience = and capabilities and also because of his demonstrated = ability to put together competent teams of people who = achieve world class results. he was the person who single = handedly upstaged the human genome project, lead to his = efforts and theirs being merged in a shotgun-wedding when it = became obvious that he would beat them by years if they = didn't join with him (his success, their funding :-) ), and = fwiw it's quite possibly his personal genome that was = sequenced by the project, although nobody will ever tell = you. He above all others is well aware of how little we know = about the complexities of the arcane machinery that we are = playing with (His quote some time after the successful end = of the HG project done his way " "We don't know shit") in a = world where many think that we have it all under control. = He is among the most aware of the dangers that can be = unleashed and of our inability to protect against them. And = he is the one most liable to do it. All the various possibilities that people mentioned are "on = the menu" with varying degrees of likelihood. From the = drooling pile in the corner to the humanity destroying super = scum. My exemplar would be something that combines the = characteristics of Ebola, HIV and the common cold. It = travels the world at just below the speed of sound (thanks = to Mr Borings fine products), is largely undetectable, has a = decade long incubation period so that everyone on earth = contracts it before the payload delivers and then attacks = with the efficacy of Ebola (speed and short term impact) so = that attempts to manage it are overwhelmed. With a bit of = care and 'luck' it should be able to take out the whole = human race. If Venter and co don't manage this by mistake = somebody (some of the more extreme people from eg F.O.T.E. = seem good candidates) should be able to engineer it to order = in the next decade or so. Venter is not creating life, and doesn't claim to be. He is = using the protein folding 101 super arcane magic making = utterly complex beyond our understanding tool-kit to splice = together bits and pieces to order. He has only the very very = very vaguest idea of the more complex interactions that will = occur between most of the portions of his creation - and he, = unlike most others, is well aware of this. He is the = pre-eminent expert in understanding in depth and with = insight the vastly complex nature of what he is doing. The = last two sentences are not mutually contradictory. Tremble. Venter is head of the race to destroy the race. And he knows = it. And he is running well at the front of the field and = with skill and stamina. I read the other day that most of = the top management of NATO are arguing for the need to have = pre-emptive nuclear strike capability to combat major = terrorist threats. Perhaps they'll have that ability any = week now and ... ;-). We stand on the bridge at Khazad-d=FBm. The not distant enough = drums sound their doom-doom call ... Don't any of you watch fine NZ movies? :-) Russell > = > http://www.wired.com/science/discoveries/news/2008/01/synthetic_genome?cu= rrentPage=3Dall -- = http://www.piclist.com PIC/SX FAQ & list archive View/change your membership options at http://mailman.mit.edu/mailman/listinfo/piclist