I realized I should probably better define what I'm looking for, so I can get more useful answers. I guess this is one area where I can't just say "how do I isolate an analog input". Not to say that the answers so far haven't be useful, as they have pointed me in some directions I haven't thought about - for instance both the V/F and the Instrument amplifier are good ideas which I will delve into further. That said, what I really need to be able to do is have a half dozen or so "voltmeters" which are attached to the PIC18F*J60. Cost is definately an object in this case. Although I will need to deal with different scales so that a 2V signal can be read with enough resolution, on the high end I need to measure up to about 60VDC. The input can swing either way. These will be used to measure things like battery voltage level (typically the *same* array that the unit is powered from, but not always), charge/discharge current measured as shunt voltage (may be on the + or - side of the bat), and other inputs such as fuel level, valve positions, etc. In many cases I could say "everything is measured in relation to ground/Vss", and this wouldn't pose a problem. In others, this would be an issue. In an ideal world, the inputs would be completely isolated from each other and from ground/Vss. That is, work just like multiple battery powered voltmeters. I realize that this may be unworkable or significantly expensive. As a result, the needs may be able to be redefined such that everything must be ground referenced. However, being able to measure voltages where the input is below Vss is important since one of the main applications for this device is to monitor battery utilization. Hopefully this rambling helps describe what I'm trying to figure out. I'm at the "we need to be able to measure x, and what are our options to do so" stage so I really don't want to through any ideas out at this point, even if they don't fully meet my ideal situation. -forrest -- http://www.piclist.com PIC/SX FAQ & list archive View/change your membership options at http://mailman.mit.edu/mailman/listinfo/piclist