I was following this thread, and went to work yesterday (I service MRI/CT scanners) to find the research people working with a watercooled thermode. ( http://www.medoc-web.com/thermode.html ). The peltier device heats up to cause pain, and the water cooling can rapidly change the temperature on it. The cable to the thermode has power for the peltier, a connection that looks like a thermocouple connector, and the feed/return water lines. There is a small (1ft x1 ft x1ft) water chiller that has the water at about 6 degs C. (An abnormal response to pain stimulus is an indicator of neurological dysfunction - or something like that) -- http://www.piclist.com PIC/SX FAQ & list archive View/change your membership options at http://mailman.mit.edu/mailman/listinfo/piclist