>The design will be implemented in a few thousands
>of boards, so it must be REALLY price optimized.

Do not forget to include the cost of doing the radiation characterisation in
the price optimisation :)

It may be that you are better to do the controller design in VHDL and put it
in an FPGA with suitable fine geometry internal structures to get the
radiation hardness (see my comment about 0.25 micron geometries). This
should certainly be a price competitive way to go if needing to build
several thousand units.

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