All the pressure transducers I used (Lucas NovaSensor), requires from 1 to 2mA (constant current) for bridge excitation, and it has an impedance around 3500 Ohms, so it will generate from 3.5 to 7 Volts across the bridge. The bridge output sits in the middle of that voltage, with a full scale around 100mV, 200mV or other. If using 5Vdc to generate the constant current, any instrumentation amplifier (+5Vdc and Ground) will be able to deal with the common voltages. But for some arrange like that I would *not* use a step up power supply based on a single transistor and a coil, instead I would go to a Maxim641 and a coil. But why the old 641? Because it is one of the few that has an internal FET *and catch diode*, and an output to drive large FET switchers, without much fuzz. It also regulate the output voltage to a fixed value, without any further regulation. I use also the Max857 with no complain at all, it has the internal FET switcher, requires the external Schokkty catcher diode and it can not drive an external N channel FET switcher. If you are interested to see this one drawing, click here: http://www.ustr.net/offers/board1diags.htm and click over the second drawing. Wagner.